Publications
Modeling the inflammatory response in the hypothalamus ensuing heat stroke: Iterative cycle of model calibration, identifiability analysis, experimental design and data collection. MATHEMATICAL BIOSCIENCES. 260:35-46.
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2015. Importance of input perturbations and stochastic gene expression in the reverse engineering of genetic regulatory networks: Insights from an identifiability analysis of an in silico network. GENOME RESEARCH. 13:2396-2405.
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2003. Real-Time Hypoglycemia Prediction Suite Using Continuous Glucose Monitoring A safety net for the artificial pancreas. DIABETES CARE. 33:1249-1254.
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2010. Glucose control design using nonlinearity assessment techniques. AICHE JOURNAL. 51:544-554.
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2005. Analysis of cellular response to protein overexpression. IEE PROCEEDINGS SYSTEMS BIOLOGY. 152:285-289.
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2005. Robustness properties of circadian clock architectures. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 101:13210-13215.
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2004. Analysis of linear programming in model predictive control. COMPUTERS & CHEMICAL ENGINEERING. 28:2749-2763.
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2004. Population balance PSD model for emulsion polymerization with steric stabilizers. AICHE JOURNAL. 49:1392-1404.
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2003. Analysis of unfolded protein response during single-chain antibody expression in Saccaromyces cerevisiae reveals different roles for BiP and PDI in folding. METABOLIC ENGINEERING. 7:269-279.
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2005. Model predictive control of continuous drum granulation. JOURNAL OF PROCESS CONTROL. 19:615-622.
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2009. Automatic Control in Systems Biology. SPRINGER HANDBOOK OF AUTOMATION. :1335-1360.
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2009. Glucose Sensing in the Peritoneal Space Offers Faster Kinetics Than Sensing in the Subcutaneous Space. DIABETES. 63:2498-2505.
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2014. An Advisory Protocol for Rapid- and Slow-Acting Insulin Therapy Based on a Run-to-Run Methodology. DIABETES TECHNOLOGY & THERAPEUTICS. 12:555-565.
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2010. Outpatient Closed-Loop Control with Unannounced Moderate Exercise in Adolescents Using Zone Model Predictive Control. DIABETES TECHNOLOGY & THERAPEUTICS. 19:331-339.
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2017. Application of Zone Model Predictive Control Artificial Pancreas During Extended Use of Infusion Set and Sensor: A Randomized Crossover-Controlled Home-Use Trial. DIABETES CARE. 40:1096-1102.
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2017. Theoretical analysis of insulin-dependent glucose uptake heterogeneity in 3D bioreactor cell culture. BIOTECHNOLOGY PROGRESS. 28:833-845.
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2012. A two-level discretisation algorithm for the efficient solution of higher-dimensional population balance models. CHEMICAL ENGINEERING SCIENCE. 63:1304-1314.
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2008. Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk. BMC SYSTEMS BIOLOGY. 4
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2010. Prevention of Nocturnal Hypoglycemia Using Predictive Alarm Algorithms and Insulin Pump Suspension. DIABETES CARE. 33:1013-1017.
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2010. A feasible solution technique for higher-dimensional population balance models. COMPUTERS & CHEMICAL ENGINEERING. 31:1242-1256.
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2007. Estimating optimal profiles of genetic alterations using constraint-based models. BIOTECHNOLOGY AND BIOENGINEERING. 89:243-251.
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2005. Model-based blood glucose control for Type 1 diabetes via parametric programming. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING. 53:1478-1491.
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2006. Unconventional systems analysis problems in molecular biology: a case study in gene regulatory network modeling. COMPUTERS & CHEMICAL ENGINEERING. 29:547-563.
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2005. Weakly Circadian Cells Improve Resynchrony. PLOS COMPUTATIONAL BIOLOGY. 8
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2012. Multi-objective blood glucose control for type 1 diabetes. MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING. 47:343-352.
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2009.